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Is dry eye associated with acquired aponeurogenic blepharoptosis?

Orbit 2014, vol. 33, issue 3


To study the relation between signs of dry eye and acquired aponeurogenic blepharoptosis.


Prospective case-control study in which 100 patients with uni-or bilateral acquired aponeurogenic blepharoptosis were matched for age and gender to 100 controls. The margin-reflex distance (MRD), the Schirmer-1 score, the duration of the tear film break up time (BUT), and the presence of any corneal staining with fluorescein were evaluated in both groups and compared. Data were analysed using either Fisher's exact test or linear regression.


The Schirmer-1 score was


(1) Compared to matched controls, patients with acquired aponeurogenic blepharoptosis more often have a decreased aqueous tear production (as measured by a Schirmer-1 test). Although a low tear production may have a causative role in the etiology of acquired blepharoptosis, it may also be explained by a dampened reflex in blepharoptosis patients (2) With age, the MRD as well as the Schirmer-1 score decrease in both groups.

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