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2016-04: Polarization-sensitive optical coherence tomography for imaging of the retinal nerve fiber layer

Glaucoma
Imaging
Investigator Initiated Research
Inclusion open since 7-6-2017

The retinal nerve fiber layer (RNFL) has unique polarization properties which can be measured and quantified by polarization sensitive OCT (PS-OCT). These properties are induced by the microtubules in the ganglion cell axons. It is hypothesized that the microtubule density is related to the RNFL’s health and is affected in glaucoma before actual thinning of the RNFL occurs. Measuring polarization properties of the RNFL could therefore provide information on glaucomatous damage at an early stage. Polarization characteristics of other retinal tissue will be explored for various ocular conditions as well.

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