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2005-20: GDx-VCC scan of the retinal nerve fibre layer as an auxiliary tool to assess the prognosis of various types of Multiple Sclerosis

Neuro-ophthalmology
Medical devices and techniques
Investigator Initiated Research
Inclusion open since 1-1-2006

Because the optic nerve is easily accessible to diagnostic scan techniques, examination of retinal nerve fibers may provide a more general picture of demyelination processes elsewhere in the CNS. In this study nerve fiber thickness will be measured with the GDx-VCC to establish whether a relationship with RR and PP stages of MS can be demonstrated.

In 150 Patients diagnosed with multiple sclerosis MS patients will by classified according to type of MS , duration of MS and degree of disability, visual acuity, visual field retinal nerve fiber thickness, intraocular pressure and OCT will be assessed. If a significant difference between various stages of MS can be demonstrated, annual visits are scheduled during a follow-up of 5 years to monitor progression.

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