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2017-27: ALLOGENEIC SERUM MICRO EYE DROPS COMPARED TO CONVENTIONAL SIZED EYE DROPS: A PROSPECTIVE RANDOMIZED NON-INFERIORITY, INVESTIGATOR-MASKED, CROSS-OVER MULTICENTER CLINICAL STUDY

Cornea and infections
Drug research
Investigator Initiated Research
Inclusion open since 1-1-2019

Serum eye drops (SEDs) are used to treat patients with severe signs and symptoms of dry eyes and other corneal defects. Serum is used in severe ophthalmic cases where conventional treatment and/or eye drops (artificial tears) have insufficient effect. The use of SEDs in dry eye patients usually has a rapid effect.

For application of eye drops, generally administration systems with a drop size of 40 to 50 μl are used,. From previous studies done with medicinal eye drops, it has been shown that smaller eye drops can be just as effective. This study will compare the feasibility and effectiveness of allogeneic serum micro eye drops using the mu-Drop applicator to the conventional sized allogeneic eye drops using the Meise applicator.

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