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2018-16: Pathogenesis, prognostic factors, clinical spectrum and response to treatment of Central serous chorioretinopathy (CSC)

Medical retina
Investigator Initiated Research
Inclusion open since 2-4-2019

Central serous chorioretinopathy (CSC) is a common form of macular degeneration characterized by the presence of subretinal fluid (SRF), most often found subfoveally. In some cases there is spontaneous resolution of SRF, but if not and left untreated it will result in irreversible vision loss. Although CSC is a common disease, at present our knowledge on the pathogenesis of CSC is scarce. In clinical studies CSC is divided in an acute and a chronic disease, however there are no clear cut of points and in every day practise CSC seems a continuum. We have established a list of 1500 patients seen at the Rotterdam Eye Hosptial with CSC and like to further study these cases for a better understanding of the pathogenesis, prognostic factors, clinical spectrum and response to treatment. Specific subgroups of CSC cases will also be analysed, for example CSC cases with a myopic refraction.

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