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2018-19: Clinical evaluation of ocular MRI for ophthalmic conditions

Investigator Initiated Research
Inclusion open since 16-1-2019

Magnetic Resonance Imaging (MRI) offers many new diagnostic possibilities for ophthalmic conditions. One of its main advantages is the ability to assess non-transparent tissues, which cannot be imaged with the standard optical techniques that are used in ophthalmology. The motion-sensitivity of MRI has precluded wide-spread use of in ophthalmology, as eye-motion is difficult to prevent. New MRI-methods have effectively solved this problem, allowing the use of MRI as a diagnostic tool in ophthalmology. However, its effectivity in doing so has yet to be evaluated for several ophthalmic conditions.

The primary objective of this pilot study is to determine the clinical value of ocular MRI for patients with the following ophthalmic conditions: 1) Glaucoma treated with a Baerveldt implant, 2) Visual field defects, 3) Diplopia.

All subjects will receive an ocular MRI-scan. For one group of subjects, subjects who have been treated with a Baerveldt implant for Glaucoma, additional measurements will be performed at the Rotterdam Eye Hospital. The clinical value of the additional diagnostic information as provided by the MRI-scans will be assessed in a multidisciplinary setting by an ophthalmologist and radiologist.

Based on the results of this pilot study, the ocular conditions for which MRI can improve the care will be selected. For these conditions a subsequent larger study will be performed to provide a more solid assessment of it additional value.

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