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2019-11: Retrospective study of epidemiology and risk factors of keratitis by Fusarium and Acanthamoeba in the Netherlands

Cornea and infections
Investigator Initiated Research
Inclusion open since 1-7-2019

Keratitis is frequently associated with use of contact lenses (CL). Among CL users, the most frequent etiology is bacterial (in particular due to Pseudomonas aeruginosa and Serratia) followed by fungi -such as Fusarium- and by Acanthamoeba. CL use is the most important risk factor for these non-bacterial pathogens in countries with temperate climates. Objectives: to assess if keratitis by Fusarium and Acanthamoeba has increased in the Netherlands (2005 to 2018), to generate hypotheses with respect to potential risk factors, and to describe clinical presentation, clinical diagnosis, laboratory diagnosis, treatment and disease outcomes.

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