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2009-16: Towards the aetiology of Seasonal Hyper Acute Panuveitis (SHAPU)

Medical retina
Molecular biology
Investigator Initiated Research
Inclusion open since 1-1-2010

Seasonal Hyper Acute Panuveitis (SHAPU) is a rare, severe inflammatory disease first described in 1984 by Upadhyay. It has only been seen and described in Nepal, mostly in immune-competent children in the age group of less than five years living in the Pokhara region. In most cases SHAPU leads to blindness. During an epidemic, 12-20 SHAPU patients visit the Pokhara Eye Hospital. The aetiology of this inflammation is still unknown. The aim of this diagnostic study is to determine the aetiology and pathology of SHAPU.

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