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2009-26: Early treatment of central serous retinopathy by photodynamic therapy: A randomized controlled trial.

Medical retina
Drug research
Investigator Initiated Research
Inclusion stopped on 4-7-2018

There is no agreement concerning the early treatment of central serous retinopathy (CSR). This protocol proposes a randomized controlled trial in patients with CSR with poor prognostic factors. Patients will be randomized between an observational and an early PDT treatment arm. In the observational arm, patients with persistent lesions at three months will be treated with PDT in agreement with current standard of care. This is a prospective randomized controlled trial to study the effect of early treatment of patients presenting with CSR (N=50) with poor prognostic factors. The main study endpoint is visual acuity at one year. Secondary study endpoints include metamorphopsia, color vision, recurrence, presence of persistent subretinal fluid on OCT and lesion size on autofluorescence imaging.

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