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2012-23: Is hypermetropia an important risk factor for primary angle-closure glaucoma in the Netherlands?

Glaucoma
Outcome research
Investigator Initiated Research
Inclusion open since 1-1-2013

If Primary angle-closure glaucoma (PACG) is detected in an early stage, blindness can be prevented by laser peripheral iridotomy (LPI). Several risk factors have been identified, such as older age, female gender, shallow anterior chamber depth (ACD) and short axial length (AL). However, the role of hypermetropia remains unclear. We hypothesise that hypermetropia is the most important risk factor for PACG based on clinical findings. Risk factors for PACG in the Netherlands have not been studied previously. In this observational case-control study we investigated patients diagnosed with PACG that received LPI in the period of 2008-2012. Exclusion criteria are cataract surgery before LPI and secondary glaucoma. The control group consists of cataract patients of comparable demographics. The primary study endpoint is the proportion of hypermetropic patients in both study groups (i.e. PACG versus controls).

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