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2013-03: Reliability and accuracy of temporal contrast sensitivity as a tool to assess presence of dry age-related macular degeneration using the C-Quant device

Cataract
Medical devices and techniques
Investigator Initiated Research
Inclusion stopped on 23-3-2015

When cataract leads to impairment of visual acuity (VA), one of the goals of cataract surgery is to restore VA. Co-morbid eye- or brain disease (e.g. glaucoma, age-related macular degeneration (AMD), retinitis pigmentosa or amblyopia) may preclude optimal VA after cataract surgery. Currently, no objective measurement exists to assess whether impaired VA is solely due to cataract, or at least partly attributable to pathology of retinal or neuronal processing. Temporal contrast sensitivity (TCS) comprises the sensitivity of the visual system to contrast change in time (as opposed to contrast change in space). Studies have shown that TCS decreases when retinal pathology is present, whereas impairment of eye optics (e.g. cataract) have no influence on TCS. If this is true, TCS could be applied to predict postoperative VA in surgically treated cataract patients. In this study we investigate first the repeatability, reproducibility and ROC area under the curve in a prospective non-interventional cohort study.

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