2013-11: External forces on the ocular surface and intraocular pressure.
Glaucoma is the most frequent cause of irreversible blindness in the world. Increased intra-ocular pressure (IOP) is the main risk-factor for development (and progression) of glaucoma. It is currently unknown how much IOP is affected during sleep with the pillow pressed against face and eyelids. The pressure increase will be measured when subjects lie horizontally with their heads resting normally on their own pillows, assuming a posture similar to during sleep. In this study we investigate whether externally induced increases in epipalpebral pressure (EPP) relate to clinically significant increases in IOP and secondary, to determine posture dependency of EPP.