2009-09: Is Intentional Continuous Shallowing of the Anterior Chamber (ICSAC) a safe procedure? Does it cause endothelial cell damage?
Removal of vitreous near sclerotomies without touching the lens is facilitated by intentional continuous shallowing of the anterior chamber (ICSAC). Thus, the risk of sclerotomy related complications can be reduced. It is unknown whether ICSAC poses a risk to the corneal endothelium. The objective of this study is to compare the effect on the corneal endothelium of ICSAC during vitrectomy. This is a randomized, comparative, open-label, parallel including patients who require vitreoretinal surgery to compare the effect of ICSAC during vitrectomy versus no ICSAC during vitrectomy, measured as endothelial cell density at 1 and 3 months.