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2010-17: Clonidine as an adjuvant to prolong local anaesthesia in ophthalmic surgery with cryocoagulation. A randomized, controlled, double-blind trial.

Surgical retina
Drug research
Investigator Initiated Research
Inclusion open since 6-7-2011

Clonidine, as an adjuvant in neuraxial local anaesthesia, is generally recognized to prolong motor block and analgesia. It is conjectured to have a similar effect on peripheral nerves and, thus, might help to reduce post-operative pain and use of analgesics. The objective of this randomized, controlled, double-blind trial is to determine the beneficial effect of a single dose of 150 μg clonidine as an adjuvant to chirocaine in retrobulbar block. Patients with indication for retinal cryocoagulation and episcleral explant, or cryocoagulation of ciliary body are eligible to participate in this study. The main study parameters are the maximal pain level, time of maximal post-operative pain, amount of escape medication used, time of use.

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