2009-05: Intraocular straylight in patients with retinitis pigmentosa.
Glare disturbance may have a substantial contribution to the visual disability of retinitis pigmentosa (RP) patients. The origin of disability glare in RP patients, optical and/or retinal factors, is unclear. Disability glare in RP patients has been hypothesized to result from subclinical (posterior subcapsular) cataract formation. Another explanation may be an aggravation of normal glare effects due to retinal degradation. In case of a cumulative effect, the relative contributions of optical and retinal factors are unknown. Knowledge about the relative contributions of optical and retinal factors to disability glare in RP will be useful in the clinical setting. The straylight parameter could be a valuable tool to monitor additional visual disability caused by cataract formation and to predict the possible benefit of (early) cataract surgery. This is an observational cross-sectional study to determine the prevalence of disability glare in RP patients; to identify the origin(s) of disability glare in RP patients and to establish the clinical value of straylight measurements in RP patients.