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2013-32: AGEYE (Ageing Eye project 9) - Intraocular scattering through different optical designs

Cataract
Medical devices and techniques
Investigator Initiated Research
Inclusion open since 1-3-2014

In cataract surgery, once the opacified crystalline lens has been removed and replaced with an artificial intraocular lens (IOL), straylight values are significantly lower than preoperative ones. However, they are still higher than expected (i.e., higher than those found in subjects whose eyes have a clear crystalline lens). Thus an unexpected and unexplained optical disturbance after cataract surgery results. The aim of this study is to elucidate factors that cause these unexplained effects. The project focuses on factors of the implant lenses as well as on intrinsic factors of the patient’s eye and surgical factors. The study on lens factors includes techniques that measure IOLs' optical quality both in vivo and in vitro, in order to determine sources of increased intraocular scatter in pseudophakic eyes. These results will be used to simulate visual quality of different optical designs and to model the optical design of lenses to reduce light scattering. The study towards patient factors will concentrate on the surgical procedure and the patients physical reaction on the procedure, in order to determine sources of increased intraocular scatter in pseudophakic eyes.

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